OCD: Psychotherapy vs. Control

Yingying Wang

, Clara Miguel

, Marketa Ciharova

, Arpana Amarnath

, Jingyuan Lin

, Ruiying Zhao

, Marieke B.J. Toffolo

, Sascha Y. Struijs

, Leonore M. de Wit

, Pim Cuijpers

General Description

The ocd-psyctr dataset is a meta-analytic research domain MARD on psychotherapy for adults with obsessive-compulsive disorder (OCD). This MARD is part of the Metapsy project. The dataset contains study information and effect size data of trials that report the effect of psychotherapy on OCD symptoms.

This dataset includes psychotherapy vs. control (‘psy vs ctr’) comparisons. Effect sizes are provided for outcomes at post-test. The protocol describing the main meta-analytic project using the database can be accessed here.

The dataset follows the Metapsy data standard. All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).

Affiliated Institutions

Vrije Universiteit Amsterdam

Online Meta-Analysis Tool

A simplified version of this database can be analyzed at metapsy.org/database/sad.

Metadata

metapsyData Shorthand: ocd-psyctr
Number of Studies: 47
Latest Version: 24.0.1
Last updated: January 8, 2024
Last search: January 1, 2023
Search String (Latest Version): ↗
Data Repository (Latest Version): ↗
Preregistration (Research Domain): ↗
License: ODC-By v1.0 ↗
Database DOI:

Version 24.0.1 (January 8, 2024):
Version 24.0.0 (January 8, 2024):

Variable Description

Variable	Description
`study`	Author of the study
`year`	Year of the study
`es`	calculated effect size
`se`	standard error of the calculated effect size
`condition_arm1`	condition in the first arm (cbt = cognitive-behavioral therapy, pst = problem-solving therapy)
`trggrp`	target group

Study References

Alcolado,2016: Alcolado, G. M., & Radomsky, A. S. (2016). A novel cognitive intervention for compulsive checking: Targeting maladaptive beliefs about memory. Journal of Behavior Therapy and Experimental Psychiatry, 53, 75-83.
Anderson,2007: Anderson, R. A., & Rees, C. S. (2007). Group versus individual cognitive-behavioural treatment for obsessive-compulsive disorder: a controlled trial. Behav Res Ther, 45(1), 123-137.
Andersson,2012: Andersson, E., Enander, J., Andrén, P., Hedman, E., Ljótsson, B., Hursti, T., . . . Rück, C. (2012). Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial. Psychol Med, 42(10), 2193-2203.
Barrett,2003: Barrett, P., Healy, L., & March, J. S. (2003). Behavioral avoidance test for childhood obsessive-compulsive disorder: A home-based observation. American Journal of Psychotherapy, 57(1), 80-100.
Barrett,2004: Barrett, P., Healy-Farrell, L., & March, J. S. (2004). Cognitive-behavioral family treatment of childhood obsessive-compulsive disorder: a controlled trial. J Am Acad Child Adolesc Psychiatry, 43(1), 46-62.
Bolton-Perrin,2008: Bolton, D., & Perrin, S. (2008). Evaluation of exposure with response-prevention for obsessive compulsive disorder in childhood and adolescence. J Behav Ther Exp Psychiatry, 39(1), 11-22.
Bolton,2011: Bolton, D., Williams, T., Perrin, S., Atkinson, L., Gallop, C., Waite, P., & Salkovskis, P. (2011). Randomized controlled trial of full and brief cognitive-behaviour therapy and wait-list for paediatric obsessive-compulsive disorder. J Child Psychol Psychiatry, 52(12), 1269-1278.
Braga,2016: Braga, D. T., Abramovitch, A., Fontenelle, L. F., Ferrão, Y. A., Gomes, J. B., Vivan, A. S., . . . Cordioli, A. V. (2016). Neuropsychological predictors of treatment response to cognitive behavioral group therapy in obsessive-compulsive disorder. Depress Anxiety, 33(9), 848-861.
Challacombe,2017: Challacombe, F. L., Salkovskis, P. M., Woolgar, M., Wilkinson, E. L., Read, J., & Acheson, R. (2017). A pilot randomized controlled trial of time-intensive cognitive–behaviour therapy for postpartum obsessive–compulsive disorder: Effects on maternal symptoms, mother–infant interactions and attachment. Psychological Medicine, 47(8), 1478-1488.
Cordioli,2003: Cordioli, A. V., Heldt, E., Bochi, D. B., Margis, R., De Sousa, M. B., Tonello, J. F., . . . Kapczinski, F. (2003). Cognitive-behavioral group therapy in obsessive-compulsive disorder: A randomized clinical trial. Psychotherapy and Psychosomatics, 72(4), 211-216.
Fals-Stewart-Schafer,1992: Fals-Stewart, W., & Schafer, J. (1992). The treatment of substance abusers diagnosed with obsessive-compulsive disorder: an outcome study. J Subst Abuse Treat, 9(4), 365-370.
Foa,2005: Foa, E. B., Liebowitz, M. R., Kozak, M. J., Davies, S., Campeas, R., Franklin, M. E., . . . Tu, X. (2005). Randomized, placebo-controlled trial of exposure and ritual prevention, clomipramine, and their combination in the treatment of obsessive-compulsive disorder. Am J Psychiatry, 162(1), 151-161.
Freeman,2008: Freeman, J. B., Garcia, A. M., Coyne, L., Ale, C., Przeworski, A., Himle, M., . . . Leonard, H. L. (2008). Early childhood OCD: Preliminary findings from a family-based cognitive-behavioral approach. Journal of the American Academy of Child & Adolescent Psychiatry, 47(5), 593-602.
Freeman,2014: Freeman, J., Sapyta, J., Garcia, A., Compton, S., Khanna, M., Flessner, C., . . . Benito, K. (2014). Family-based treatment of early childhood obsessive-compulsive disorder: The Pediatric Obsessive-Compulsive Disorder Treatment Study for Young Children (POTS Jr)—A randomized clinical trial. JAMA psychiatry, 71(6), 689-698.
Freeston,1997: Freeston, M. H., Ladouceur, R., Gagnon, F., Thibodeau, N., Rhéaume, J., Letarte, H., & Bujold, A. (1997). Cognitive-behavioral treatment of obsessive thoughts: a controlled study. J Consult Clin Psychol, 65(3), 405-413.
Gomes,2016: Gomes, J. B., Cordioli, A. V., Bortoncello, C. F., Braga, D. T., Gonçalves, F., & Heldt, E. (2016). Impact of cognitive-behavioral group therapy for obsessive-compulsive disorder on family accommodation: A randomized clinical trial. Psychiatry Res, 246, 70-76.
Greist,2002: Greist, J. H., Marks, I. M., Baer, L., Kobak, K. A., Wenzel, K. W., Hirsch, M. J., . . . Clary, C. M. (2002). Behavior therapy for obsessive-compulsive disorder guided by a computer or by a clinician compared with relaxation as a control. J Clin Psychiatry, 63(2), 138-145.
Herbst,2014: Herbst, N., Voderholzer, U., Thiel, N., Schaub, R., Knaevelsrud, C., Stracke, S., . . . Külz, A. K. (2014). No talking, just writing! Efficacy of an Internet-based cognitive behavioral therapy with exposure and response prevention in obsessive compulsive disorder. Psychother Psychosom, 83(3), 165-175.
Khodarahimi,2009: Khodarahimi, S. (2009). Satiation therapy and exposure response prevention in the treatment of obsessive compulsive disorder. Journal of Contemporary Psychotherapy, 39(3), 203-207.
Kobayashi,2020: Kobayashi, Y., Kanie, A., Nakagawa, A., Takebayashi, Y., Shinmei, I., Nakayama, N., . . . Mimura, M. (2020). An evaluation of family-based treatment for OCD in Japan: a pilot randomized controlled trial. Frontiers in Psychiatry, 10, 932.
Kyrios,2018: Kyrios, M., Ahern, C., Fassnacht, D. B., Nedeljkovic, M., Moulding, R., & Meyer, D. (2018). Therapist-Assisted Internet-Based Cognitive Behavioral Therapy Versus Progressive Relaxation in Obsessive-Compulsive Disorder: Randomized Controlled Trial. J Med Internet Res, 20(8), e242.
Launes,2019: Launes, G., Hagen, K., Sunde, T., Öst, L.-G., Klovning, I., Laukvik, I.-L., . . . Hansen, B. (2019). A randomized controlled trial of concentrated ERP, self-help and waiting list for obsessive-compulsive disorder: the Bergen 4-day treatment. Frontiers in Psychology, 10, 2500.
Lenhard,2017: Lenhard, F., Andersson, E., Mataix-Cols, D., Rück, C., Vigerland, S., Högström, J., . . . Serlachius, E. (2017). Therapist-Guided, Internet-Delivered Cognitive-Behavioral Therapy for Adolescents With Obsessive-Compulsive Disorder: A Randomized Controlled Trial. J Am Acad Child Adolesc Psychiatry, 56(1), 10-19.e12.
Lewin,2014: Lewin, A. B., Park, J. M., Jones, A. M., Crawford, E. A., De Nadai, A. S., Menzel, J., . . . Storch, E. A. (2014). Family-based exposure and response prevention therapy for preschool-aged children with obsessive-compulsive disorder: a pilot randomized controlled trial. Behav Res Ther, 56, 30-38.
Lindsay,1997: Lindsay, M., Crino, R., & Andrews, G. (1997). Controlled trial of exposure and response prevention in obsessive-compulsive disorder. Br J Psychiatry, 171, 135-139.
Mancebo,2021: Mancebo, M. C., Yip, A. G., Boisseau, C. L., Rasmussen, S. A., & Zlotnick, C. (2021). Behavioral Therapy Teams for Obsessive-Compulsive Disorder: Lessons Learned From a Pilot Randomized Trial in a Community Mental Health Center. Behav Ther, 52(5), 1296-1309.
Mathur,2021: Mathur, S., Sharma, M. P., Balachander, S., Kandavel, T., & Reddy, Y. C. J. (2021). A randomized controlled trial of mindfulness-based cognitive therapy vs stress management training for obsessive-compulsive disorder. Journal of Affective Disorders, 282, 58-68.
Matsumoto,2022: Matsumoto, K., Hamatani, S., Makino, T., Takahashi, J., Suzuki, F., Ida, T., . . . Omori, I. M. (2022). Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan. Internet interventions, 28, 100515.
Norman,2021: Norman, L. J., Mannella, K. A., Yang, H., Angstadt, M., Abelson, J. L., Himle, J. A., . . . Taylor, S. F. (2021). Treatment-Specific Associations Between Brain Activation and Symptom Reduction in OCD Following CBT: A Randomized fMRI Trial. Am J Psychiatry, 178(1), 39-47.
O'Connor,1999: O'Connor, K., Todorov, C., Robillard, S., Borgeat, F., & Brault, M. (1999). Cognitive-behaviour therapy and medication in the treatment of obsessive-compulsive disorder: a controlled study. The Canadian Journal of Psychiatry, 44(1), 64-71.
O'Connor,2006: O'Connor, K. P., Aardema, F., Robillard, S., Guay, S., Pélissier, M. C., Todorov, C., . . . Doucet, P. (2006). Cognitive behaviour therapy and medication in the treatment of obsessive-compulsive disorder. Acta Psychiatr Scand, 113(5), 408-419.
Piacentini,2011: Piacentini, J., Bergman, R. L., Chang, S., Langley, A., Peris, T., Wood, J. J., & McCracken, J. (2011). Controlled comparison of family cognitive behavioral therapy and psychoeducation/relaxation training for child obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry, 50(11), 1149-1161.
POST,2004: Team, P. O. T. S. P. (2004). Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder: the Pediatric OCD Treatment Study (POTS) randomized controlled trial. Jama, 292(16), 1969-1976.
Rezvan,2013: Rezvan, S., Bahrami, F., Abedi, M., Macleod, C., Doost, H. T. N., & Ghasemi, V. (2013). A preliminary study on the effects of attachment-based intervention on pediatric obsessive-compulsive disorder. International journal of preventive medicine, 4(1), 78.
Rupp,2019: Rupp, C., Jürgens, C., Doebler, P., Andor, F., & Buhlmann, U. (2019). A randomized waitlist-controlled trial comparing detached mindfulness and cognitive restructuring in obsessive-compulsive disorder. PLoS One, 14(3), e0213895.
Russell,2013: Russell, A. J., Jassi, A., Fullana, M. A., Mack, H., Johnston, K., Heyman, I., . . . Mataix-Cols, D. (2013). Cognitive behavior therapy for comorbid obsessive-compulsive disorder in high-functioning autism spectrum disorders: a randomized controlled trial. Depress Anxiety, 30(8), 697-708.
Russman Block,2023: Russman Block, S., Norman, L. J., Zhang, X., Mannella, K. A., Yang, H., Angstadt, M., . . . Fitzgerald, K. D. (2023). Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial. Am J Psychiatry, 180(1), 89-99. doi:10.1176/appi.ajp.21111173
Storch,2011: Storch, E. A., Caporino, N. E., Morgan, J. R., Lewin, A. B., Rojas, A., Brauer, L., . . . Murphy, T. K. (2011). Preliminary investigation of web-camera delivered cognitive-behavioral therapy for youth with obsessive-compulsive disorder. Psychiatry Res, 189(3), 407-412.
Twohig,2010: Twohig, M. P., Hayes, S. C., Plumb, J. C., Pruitt, L. D., Collins, A. B., Hazlett-Stevens, H., & Woidneck, M. R. (2010). A randomized clinical trial of acceptance and commitment therapy versus progressive relaxation training for obsessive-compulsive disorder. J Consult Clin Psychol, 78(5), 705-716.
van-Balkom,1998: van Balkom, A. J., de Haan, E., van Oppen, P., Spinhoven, P., Hoogduin, K. A., & van Dyck, R. (1998). Cognitive and behavioral therapies alone versus in combination with fluvoxamine in the treatment of obsessive compulsive disorder. The Journal of nervous and mental disease, 186(8), 492-499.
Vogel,2014: Vogel, P. A., Solem, S., Hagen, K., Moen, E. M., Launes, G., Håland, Å. T., . . . Himle, J. A. (2014). A pilot randomized controlled trial of videoconference-assisted treatment for obsessive-compulsive disorder. Behaviour Research and Therapy, 63, 162-168.
Whittal,2010: Whittal, M. L., Woody, S. R., McLean, P. D., Rachman, S. J., & Robichaud, M. (2010). Treatment of obsessions: a randomized controlled trial. Behav Res Ther, 48(4), 295-303.
Wilhelm,2009: Wilhelm, S., Steketee, G., Fama, J. M., Buhlmann, U., Teachman, B. A., & Golan, E. (2009). Modular cognitive therapy for obsessive-compulsive disorder: A wait-list controlled trial. Journal of Cognitive Psychotherapy, 23(4), 294-305.
Williams,2010: Williams, T. I., Salkovskis, P. M., Forrester, L., Turner, S., White, H., & Allsopp, M. A. (2010). A randomised controlled trial of cognitive behavioural treatment for obsessive compulsive disorder in children and adolescents. Eur Child Adolesc Psychiatry, 19(5), 449-456.
Wolters,2016: Wolters, L. H., de Haan, E., Hogendoorn, S. M., Boer, F., & Prins, P. J. M. (2016). Severe pediatric obsessive compulsive disorder and co-morbid autistic symptoms: Effectiveness of cognitive behavioral therapy. Journal of Obsessive-Compulsive and Related Disorders, 10, 69-77.
Wootton,2013: Wootton, B. M., Dear, B. F., Johnston, L., Terides, M. D., & Titov, N. (2013). Remote treatment of obsessive-compulsive disorder: A randomized controlled trial. Journal of Obsessive-Compulsive and Related Disorders, 2(4), 375-384.
Zejuan-Fu,2016: 符泽娟, & 谢海玲. (2016). 认知行为干预疗法对改善强迫症患者心理状态及生活质量的效果评价. 实用临床医药杂志, 20(8), 17-20.
Zhang,2021: Zhang, T., Lu, L., Didonna, F., Wang, Z., Zhang, H., & Fan, Q. (2021). Mindfulness-Based Cognitive Therapy for Unmedicated Obsessive-Compulsive Disorder: A Randomized Controlled Trial With 6-Month Follow-Up. Frontiers in Psychiatry, 12.

Database Flowchart

Studies in the ocd-psyctr dataset were extracted from the larger “psychological interventions for OCD” database. The study flow of this database can be found below.

Wrong population: n=53
Wrong design: n=133
Wrong comparators: n=144
Unguided self-help: n=12
Protocols: n=10
Trial registrations without results: n=104
Other reasons: n=62
No full-text: n=10

Citation