Psychosis: Psychotherapy vs. Control

Edel Mc Glanaghy , David Turner , Georgina A. Davis , Helen Sharpe , Nadine Dougall , Paul Morris , Wendy Prentice , Paul Hutton

General Description

The data-psychosis-psyctr dataset is a meta-analytic research domain MARD which is part of the Metapsy project. The dataset contains study information and effect size data of randomized trials on psychological interventions for schizophrenia and psychosis. The date of the last search update is provided here. More details about a larger version of this dataset can be accessed in the published network meta-analysis.

This dataset includes psychological interventions vs. control (psy vs ctr) comparisons. Effect sizes are provided for three types of outcomes at post-test: total symptoms, negative symptoms, and positive symptoms. It includes one type of effect size calculation per study, giving priority to change scores, followed by means and standard deviations at post-test.

The dataset follows the Metapsy data standard.


Affiliated Institutions

University of Edinburgh


Online Meta-Analysis Tool

A simplified version of this database can be analyzed at metapsy.org/database/psychosis.


Metadata

  • metapsyData Shorthand: psychosis-psyctr
  • Number of Studies: 80
  • Latest Version: 23.1.4
  • Last updated: March 31, 2023
  • Last search: January 1, 2017
  • Search String (Latest Version): ↗
  • Data Repository (Latest Version): ↗
  • Preregistration (Research Domain): ↗
  • License: ODC-By v1.0 ↗
  • Database DOI:

  • Version 23.1.4 (March 31, 2023):
  • Version 23.1.3 (March 31, 2023):
  • Version 23.1.2 (March 31, 2023):
  • Version 23.1.1 (March 31, 2023):
  • Version 23.1.0 (March 30, 2023):
  • Version 23.0.4 (March 29, 2023):
  • Version 23.0.3 (March 29, 2023):
  • Version 23.0.2 (March 29, 2023):
  • Version 23.0.1 (March 29, 2023):

Variable Description

VariableDescription
studyAuthor and year of publication
referenceStudy reference
condition_arm1ALL - Protocol with 4 psychotherapies combined; CBT -Cognitive behaviour therapy; CR - Cognitive remediation; CRSS - Cognitive remediation focussed on social cognition; EMDR - Eye movement desensitisation and reprocessing; FT - Family therapy; HIT - Hallucinations focused integrative therapy; MCT - Metacognitive therapy; MPE - Mindfulness-based psychoeducation; PE – Psychoeducation; SST - Social skills training; WB – Wellbeing
condition_arm2Type of comparator (TAU0= Minimal contact and/or intervention- for example, medication only with no follow up, TAU1= Medication with routine check-up appointments/follow up, TAU2= Case management and/or access to MDT services such as social work, OT and psychosocial interventions, TAU3 = TAU2 plus specified delivered psychological interventions, for example, CBT or motivational interviewing, BF= befriending, CCBF= computerised contorl befirending, CC= computerised control, SC= supportive counceling, OT= occupational therapy, CAT= cognitive adaptive therapy)
multi_arm1In multiarm trials, this variable provides a specification of the type of treatment used in the first arm. This variable is set to NA (missing) when the study was not a multiarm trial. For example, if a multiarm trial employed two types of CBT interventions, face-to-face and Internet-based, this variable would be set to f2f and Internet, respectively
multi_arm2In multiarm trials, this variable provides a specification of the type of treatment used in the second arm. This variable is set to NA (missing) when the study was not a multiarm trial. For example, if a multiarm trial employed two types of control groups, waitlist and placebo, this variable would be set to wl and plac, respectively. Typically, multiarm trials employ two or more active treatments (e.g. CBT and problem-solving therapy), which are compared to the same control group (e.g. a waitlist). This means that values in multi_arm2 do not differ (e.g. they are always wl for this specific multiarm trial); nevertheless, the variable should be specified in the dataset
compatisonComparison between the trial arms, psy= psychotherapy, and ctr= control
outcome_typeThe msd factor level is typically used for the post-intervention outcomes expressed in means and standard deviations. The change is reported when available
symptom_domainDomain of the psychotic symptom mesured with a specific instrument used in a trial (i.e., postive symptoms, negative symptoms and total symptoms)
instrumentThis variable describes the instrument through which the relevant outcome was measured in combination with the symptom domain measured with that instument
ratingThis variable encodes if the measured outcome was clinician-rated ('interviewer-rated') or caregiver-rated ('caregiver-rated')
mean_arm1Mean arm 1
mean_arm2Mean arm 2
sd_arm1Standard deviation arm 1
sd_arm2Standard deviation arm 2
n_arm1Number of participants arm 1
n_arm2Number of participants arm 2
mean_change_arm1Mean change from baseline arm 1
mean_change_arm2Mean change from baseline arm 2
sd_change_arm1Standard deviation for the change from baseline arm 1
sd_change_arm2Standard deviation for the change from baseline arm 2
n_change_arm1Number of participants arm 1 (change scores)
n_change_arm2Number of participants arm 2 (change scores)
totaln_arm1Total number of participants arm 1 (event data)
totaln_arm2Total number of participants arm 2 (event data)
N_randomized_totalTotal number of randomized participant in the trial
yearYear of publication
timeThe measurement point at which the outcome was obtained (e.g. post or follow-up)
time_weeksThe measurement point at which the outcome was obtained, in weeks after randomization (set to NA if this information was not available)
trial_lenghtTotal lenght of the trial in weeks
formatFormat of the intevention (i.e., individual, group, computer based an mixed)
n_sessions_arm1Total number of sessions in arm 1
n_sessions_arm2Total number of sessions in arm 2
countryExact country where the study was conducted
mean_ageAverage age
percent_women% of women at baseline
recruitmentInpatient; Outpatient; Both inpatient and outpatient
diagnosisInclusion diagnostic criteria
dur_ill_arm1Mean duration of the illness in years in arm 2
stageChronic/Early
clinical_pictureAcute/Stable
otherOther disorder specific notations made by the author of the trial
Selection bias; random sequence generationDomain 1 (Selection bias) - random sequence generation
Selection bias; allocation concealmentDomain 2(Selection bias) - allocation concealment
Reporting bias; selective reportingDomain 3 (Reporting bias) - selective reporting
Attrition bias; incomplete outcome dataDomain 4 (Attrition bias) - incomplete outcome data
Performance bias; blinding of ppts and personnelDomain 5(Performance bias) - blinding of ppts and personnel
Detection bias; blinding of outcome assessmentDomain 6(Detection bias) - blinding of outcome assessment
robOverall risk of bias rating (low=1 vs high=0)
.idMetapsyTools generated variable: Unique identifier for a trial arm comparison/row
.gMetapsyTools generated variable: Calculated effect size (Hedges' g)
.g_seMetapsyTools generated variable: Standard error of Hedges' g
event_arm1Number of events (responders, remission, deterioration cases) in the first trial arm
event_arm2Number of events (responders, remission, deterioration cases) in the second trial arm


Study References

  • Agothor, 2010: Aghotor J, Pfueller U, Moritz S, Weisbrod M, Roesch-ely D. Metacognitive training for patients with schizophrenia (MCT): Feasibility and preliminary evidence for its efficacy. J Behav Ther Exp Psychiatry [Internet]. Elsevier Ltd; 2010;41(3):207–11. Available from: http://dx.doi.org/10.1016/j.jbtep.2010.01.004
  • Bark 2003: Bark N, Revheim N, Huq F, Khalderov V, Watras Z, Medalia A. The impact of cognitive remediation on psychiatric symptoms of schizophrenia. Schizophr Res. 2003;63:229–35.
  • Barrowclough 2006: Barrowclough C, Haddock G, Lobban F, Jones S, Siddle RON, Roberts C, et al. Group cognitive-behavioural therapy for schizophrenia: Randomised controlled trial. Br J Psychiatry. 2006;(189):527–32.
  • Bradley 2006: Bradley GM, Couchman GM, Perlesz A, Nguyen AT, Singh B, Riess C. Multiple-family group treatment for families living with schizophrenia. Psychiatr Serv. 2006;57(4):521–30.
  • Byrne 2013: Byrne LK, Peng D, McCabe M, Mellor D, Zhang J, Zhang T, et al. Does practice make perfect? Results from a Chinese feasibility study of cognitive remediation in schizophrenia. Neuropsychol Rehabilitation. 2013;23(4):580–96.
  • Cai 2015: Cai J, Zhu Y, Zhang W, Wang Y, Zhang C. Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia. Neuropsychiatr Dis Treat. 2015;11:1247–53.
  • Chan 2009: Chan SW, Yip B, Tso S, Cheng B, Tam W. Evaluation of a psychoeducation program for Chinese clients with schizophrenia and their family caregivers. Patient Educ Couns. 2009;75:67–76.
  • Chien 2013a: Chien 2013a: Chien WT, Lee IYM. The mindfulness-based psychoeducation program for Chinese patients with schizophrenia. Psychiatr Serv. 2013;64(4).
  • Chien 2013b: Chien 2013b: Chien W-T, Leung S-F. A controlled trial of a needs-based, nurse-led psychoeducation programme for Chinese patients with first-onset mental disorders: 6 month follow up. Int J Nurs Pract. 2013;19:3–13.
  • Chien 2014: Chien WT, Thompson DR. Effects of a mindfulness-based psychoeducation programme for Chinese patients with schizophrenia: 2-year follow-up. Br J Psychiatry. 2014;205:52–9.
  • d'Amato 2011: d’Amato T, Bation R, Cochet A, Jalenques I, Galland F, Giraud-Baro E, et al. A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia. Schizophr Res. 2011;125:284–90.
  • Dickinson 2010: Dickinson D, Ph D, Tenhula W, Ph D, Morris S, Ph D, et al. A randomized , controlled trial of computer-assisted cognitive remediation for schizophrenia. Am J Psychiatry. 2010;167:170–80.
  • Durham 2003: Durham RC, Guthrie A, Morton RV, Reid DA, Treliving LR, Owler DF, et al. Tayside-Fife clinical trial of cognitive- behavioural therapy for medication-resistant psychotic symptoms; Results to 3-month follow-up. Br J Psychiatry. 2003;182:303–12.
  • England 2007: England M. Efficacy of cognitive nursing intervention for voice hearing. Perspect Psychiatr Care. 2007;43(2):69–76.
  • Färdig 2011: Färdig R, Lewander T, Melin L, Folke F, Fredriksson A. A randomized controlled trial of the Illness Management and Recovery Program for persons with schizophrenia. Psychiatr Serv. 2011;62(6):606–12.
  • Farreny 2012: Farreny A, Aguado J, Ochoa S, Huerta-ramos E, Marsà F, López-carrilero R, et al. REPYFLEC cognitive remediation group training in schizophrenia Looking for an integrative approach. Schizophr Res [Internet]. Elsevier B.V.; 2012;142(1–3):137–44. Available from: http://dx.doi.org/10.1016/j.schres.2012.08.035
  • Fernandez-Gonzalo 2015: Fernandez-Gonzalo S, Turon M, Jodar M, Pousa E, Hernandez C, García R, et al. A new computerized cognitive and social cognition training specifically designed for patients with schizophrenia/ schizoaffective disorder in early stages of illness : A pilot study. Psychiatry Res. Elsevier Ireland Ltd; 2015;228:501–9.
  • Fiszdon 2016: Fiszdon JM, Choi KH, Bell MD, Choi J, Silverstein SM. Cognitive remediation for individuals with psychosis : efficacy and mechanisms of treatment effects. Psychol Med. 2016;46:3275– 89.
  • Freeman 2015a: Freeman 2015a: Freeman D, Dunn G, Startup H, Pugh K, Cordwell J, Mander H, et al. Effects of cognitive behaviour therapy for worry on persecutory delusions in patients with psychosis (WIT): a parallel, single-blind , randomised controlled trial with a mediation analysis. Lancet Psychiatry. 2015;2(April 2015):305–13.
  • Freeman 2015b: Freeman 2015b: Freeman D, Waite F, Startup H, Myers E, Lister R, Mcinerney J, et al. Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective , assessor-blind , randomised controlled pilot trial. Lancet Psychiatry. 2015;2:975–83.
  • Garcia 2003: García S, Fuentes I, Ruíz JC, Gallach E, Roder V. Application of the IPT in a Spanish sample : Evaluation of the “Social Perception Subprogramme.” Int J Psychol Psychol Ther. 2003;3(2):299–310.
  • Garety 2008a: Garety 2008 (i) & (ii): Garety PA, Fowler DG, Freeman D, Bebbington P, Dunn G, Kuipers E. Cognitive – behavioural therapy and family intervention for relapse prevention and symptom reduction in psychosis : randomised controlled trial. Br J Psychiatry. 2008;192:412– 23.
  • GilSanz 2009: GilSanz DG, Lorenzo MD, Seco RB, Rodriguez MA, Martinez IL, Calleja RS, et al. Efficacy of a social cognition training program for schizophrenic patients : A Pilot Study. Span J Psychol. 2009;12(1):184–91.
  • Gumley 2003: Gumley A, O’Grady M, McNay L, Reilly J, Power K, Norrie J. Early intervention for relapse in schizophrenia : results of a 12-month randomized controlled trial of cognitive behavioural therapy.
  • Guo 2010: Guo X, Zhai J, Liu Z, Fang M, Wang B, Wang C, et al. Antipsychotic medication alone versus combined with psychosocial intervention on outcomes of early stage schizophrenia: a randomized, one-year study. Arch Gen Psychiatry. 2010;67(9):895–904.
  • Haddock 1999: Haddock G, Tarrier N, Morrison AP, Hopkins R, Drake R, Lewis S. A pilot study evaluating the effectiveness of individual inpatient cognitive-behavioural therapy in early psychosis. Soc Psychiatry Psychiatr Epidemiol. 1999;34:254–8.
  • Hayes 1995: Hayes RL, Halford WK, Varghese FT. Social skills training with chronic schizophrenic patients: Effects on _negative symptoms and community functioning. Behav Ther. 1995;26:433–49.
  • Jenner 2004: Jenner JA, Nienhuis FJ, Wiersma D, van de Willige G. Hallucination focused integrative treatment : A randomized controlled trial. Schizophr Bull. 2004;30(1):133–46.
  • Jørgensen 2015: Jørgensen R, Licht RW, Lysaker PH, Munk-Jørgensen P, Buck KD, Jensen SOW, et al. Effects on cognitive and clinical insight with the use of Guided Self-Determination in outpatients with schizophrenia : A randomized open trial. Eur Psychiatry. 2015;30:655–63.
  • Kang 2016: Kang R, Wu Y, Li Z, Jiang J, Gao Q, Yu Y, et al. Effect of community-based social skills training and Tai-Chi exercise on outcomes in patients with chronic schizophrenia : A randomized , one-year study. Psychopathology. 2016;49:345–55.
  • Kantrowitz 2016: Kantrowitz JT, Sharif Z, Medalia A, Keefe RSE, Harvey P, Bruder G, et al. A multicenter, rater-blinded, randomised controlled study of auditory processing-focused cognitive remediation combined with open-label Lurasidone in patients with schizphrenia and schizoaffective disorder. J Clin Psychiatry. 2016;77(6):799–806.
  • Keefe 2012: Keefe RSE, Vinogradov S, Medalia A, Peter F, Caroff SN, Souza DCD, et al. Feasibility and pilot efficacy results from the multi-site Cognitive Remediation in the Schizophrenia Trials Network (CRSTN) Study. J Clin Psychiatry. 2012;73(7):1016–22.
  • Kim 2010: Kim D, Choi J, Kim SH, Oh DH, Park S, Lee SH. A pilot study of brief Eye Movement Desensitization and Reprocessing(EMDR) for treatment of acute phase schizophrenia. Korean J Biol Psychiatry. 2010;17(2):94–102.
  • Kuipers 1997: Kuipers E, Garety PA, Fowler D, Dunn G, Bebbington P, Freeman D, et al. London-East Anglia randomised controlled trial of cognitive-behavioural therapy for psychosis. Br J Psychiatry. 1997;171:319–27.
  • Kumar 2010: Kumar D, Zia M, Haq U, Dubey I, Dotivala KN, Siddiqui SV, et al. Effect of meta-cognitive training in the reduction of _positive symptoms in schizophrenia. Eur J Psychother Couns. 2010;12(2):149–58.
  • Leclerc 2000: Leclerc C, Lesage AD, Ricard N, Lecomte T, Cyr M. Assessment of a new rehabilitative coping skills module for persons with schizophrenia. Am J Orthopsychiatry. 2000;70(3):380– 8.
  • Lee 2013CR: Lee, W K. Effectiveness of computerized cognitive rehabilitation training on symptomatological, neuropsychological and work function in patients with schizophrenia. Asia-Pacific Psychiatry, 2013; 5: 90–100.
  • Lewis 2002: Lewis S, Tarrier N, Haddock G, Bentall R, Kinderman P, Kingdon D, et al. Randomised controlled trial of cognitive-behavioural therapy in early schizophrenia : acute-phase outcomes. Br J Psychiatry. 2002;181 (suppl:s91-98.
  • Li 2015: Li Z, Guo Z, Wang N, Xu Z, Qu Y, Wang X, et al. Cognitive – behavioural therapy for patients with schizophrenia : a multicentre randomized controlled trial in Beijing , China. Psychol Med. 2015;45:1893–905.
  • Liberman 2009: Liberman RP, Kopelowicz A. Training skills for illness self-management in the rehabilitation of schizophrenia . A family-assisted program for Latinos in California. Salud Ment. 2009;31:93–105.
  • Lincoln 2012: Lincoln TM, Ziegler M, Mehl S, Kesting M, Lullmann E, Westermann S, et al. Moving from efficacy to effectiveness in Cognitive Behavioral Therapy for Psychosis : A randomized clinical practice trial. J Consult Clin Psychol. 2012;80(4):674–86.
  • Lopez-Leungo 2016: López-Luengo B, Muela-Martínez JA. Preliminary study of a rehabilitation program based on attentional processes to treat auditory hallucinations. Cogn Neuropsychiatry. Taylor & Francis; 2016;21(4):315–34.
  • Morrison 2014: Morrison AP, Turkington D, Pyle M, Spencer H, Brabban A, Dunn G, et al. Cognitive therapy for people with schizophrenia spectrum disorders not taking antipsychotic drugs : a single- blind randomised controlled trial. Lancet [Internet]. Elsevier Ltd; 2014: 383(9926):1395–403. Available from: http://dx.doi.org/10.1016/S0140-6736(13)62246-1
  • Naeem 2015: Naeem F, Saeed S, Irfan M, Kiran T, Mehmood N, Gul M, et al. Brief culturally adapted CBT for psychosis (CaCBTp): A randomized controlled trial from a low income country. Schizophr Res. 2015;164:143–8.
  • Naeem 2016: Naeem F, Johal R, Mckenna C, Rathod S, Ayub M, Lecomte T, et al. Cognitive behavior therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals : Results of a feasibility study. Schizophr Res [Internet]. Elsevier B.V.; 2016;173(1–2):69–74. Available from: http://dx.doi.org/10.1016/j.schres.2016.03.003
  • Ng 2006: Ng RMK, Cheung MSL. Social skills training in Hong Kong Chinese patients with chronic schizophrenia. Hong Kong J Pscyhiatry. 2006;16(1):14–20.
  • Ojeda 2012: Ojeda N, Pena J, Sanchez P, Bengoetxea E, Elizagarate E, Ezcurra J, et al. Efficiency of cognitive rehabilitation with REHACOP in chronic treatment resistant Hispanic patients. NeuroRehabilitation. 2012;30:65–74.
  • Omiya 2016: Omiya H, Yamashita K, Miyata T, Hatakeyama Y, Miyajima M, Yambe K, et al. Pilot study of the effects of cognitive remediation therapy using the frontal/executive program for treating chronic schizophrenia. Open Psychol J. 2016;9:121–8.
  • Penn 2009: Penn DL, Meyer PS, Evans E, Wirth RJ, Cai K, Burchinal M. A randomized controlled trial of group cognitive-behavioral therapy vs . enhanced supportive therapy for auditory hallucinations. Schizophr Res [Internet]. Elsevier B.V.; 2009;109(1–3):52–9. Available from: http://dx.doi.org/10.1016/j.schres.2008.12.009
  • Penn 2011: Penn DL, Uzenoff SR, Perkins D, Mueser KT, Hamer R, Waldheter E, et al. A pilot investigation of the Graduated Recovery Intervention Program (GRIP) for first episode psychosis. Schizophr Res [Internet]. Elsevier B.V.; 2011;125(2–3):247–56. Available from: http://dx.doi.org/10.1016/j.schres.2010.08.006
  • Peters 2010: Peters E, Landau S, Mccrone P, Cooke M, Fisher P, Steel C, et al. A randomised controlled trial of cognitive behaviour therapy for psychosis in a routine clinical service. Acta Psychiatr Scand. 2010;122:302–18.
  • Rakitzi 2016: Rakitzi S, Georgila P, Efthimiou K, Mueller DR. Efficacy and feasibility of the Integrated Psychological Therapy for outpatients with schizophrenia in Greece : Final results of a RCT. Psychiatry Res [Internet]. Elsevier; 2016;242:137–43. Available from: http://dx.doi.org/10.1016/j.psychres.2016.05.039
  • Rathod 2013: Rathod S, Phiri P, Harris S, Underwood C, Thagadur M, Padmanabi U, et al. Cognitive behaviour therapy for psychosis can be adapted for minority ethnic groups : A randomised controlled trial. Schizophr Res [Internet]. Elsevier B.V.; 2013;143(2–3):319–26. Available from: http://dx.doi.org/10.1016/j.schres.2012.11.007
  • Rector 2003: Rector NA, Seeman M V, Segal Z V. Cognitive therapy for schizophrenia : a preliminary randomized controlled trial. Schizophr Res. 2003;63:1–11.
  • Roberts 2014: Roberts DL, Combs DR, Willoughby M, Mintz J, Gibson C, Rupp B, et al. A randomized , controlled trial of Social Cognition and Interaction Training (SCIT) for outpatients with schizophrenia spectrum disorders. Br J Clin Psychol. 2014;53:281–98.
  • Rus-Calafell 2013: Rus-Calafell M, Gutiérrez-Maldonado J, Ortega-Bravo M, Ribas-Sabaté J, Caqueo-Urízar A. A brief cognitive – behavioural social skills training for stabilised outpatients with schizophrenia : A preliminary study. Schizophr Res [Internet]. Elsevier B.V.; 2013;143(2– 3):327–36. Available from: http://dx.doi.org/10.1016/j.schres.2012.11.014
  • Sánchez 2013: Sánchez P, Peña J, Bengoetxea E, Ojeda N, Elizagárate E, Ezcurra J, et al. Improvements in _negative symptoms and functional outcome after a new generation cognitive remediation program: A randomized controlled trial. Schizophr Bull. 2014;40(3):707–15.
  • Schaub 2016: Schaub A, Mueser KT, Werder T Von, Engel R, Möller H, Falkai P. A randomized controlled trial of group coping-oriented therapy vs supportive therapy in schizophrenia : Results of a 2- Year Follow-up. Schizophr Bull. 2016;42(1):s71-80.
  • Schrank 2016: Schrank B, Brownell T, Jakaite Z, Larkin C, Pesola F, Riches S, Tylee A, Slade M. Evaluation of a _positive psychotherapy group intervention for people with psychosis: pilot randomised controlled trial. Epid Psychiatric Sci. 2016; 25: 235–246.
  • Sensky 2000: Sensky T, Turkington D, Kingdon D, Scott JL, Scott J, Siddle R, et al. A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication. Arch Gen Psychiatry. 2000;57:165–72.
  • Shin 2002: Shin S-K, Lukens EP. Effects of psychoeducation for Korean Americans with chronic mental illness. Psychiatr Serv. 2002;53(9):1125–31.
  • Startup 2004: Startup M, Jackson MC, Bendix S. North Wales randomized controlled trial of cognitive behaviour therapy for acute schizophrenia spectrum disorders : outcomes at 6 and 12 months. Psychol Med. 2004;34:413–22.
  • Tan 2016: Tan S, Zou Y, Wykes T, Reeder C, Zhu X, Yang F, et al. Group cognitive remediation therapy for chronic schizophrenia : A randomized controlled trial. Neurosci Lett [Internet]. Elsevier Ireland Ltd; 2016;626:106–11. Available from: http://dx.doi.org/10.1016/j.neulet.2015.08.036
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  • Tarrier 2014: Tarrier N, Kelly J, Maqsood S, Snelson N, Maxwell J, Law H, et al. The cognitive behavioural prevention of suicide in psychosis : A clinical trial. Schizophr Res [Internet]. Elsevier B.V.; 2014;156(2–3):204–10. Available from: http://dx.doi.org/10.1016/j.schres.2014.04.029
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  • Wykes 1999: Wykes T, Reeder C, Corner J, Wuliams C, Everitt B. The effects of neurocognitive remediation on executive processing in patients with schizophrenia. Schizophr Bull. 1999;25(2):291–308.
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Database Flowchart

Studies in the psychosis-psyctr dataset were extracted from the larger database on psychological interventions for psychosis. The current dataset includes the subset of psychological interventions compared to control conditions.

(n=21856)Records identified through database searches (n=0)Records identified through other sources (n=21082)Records after duplicate removal (n=21082)Records screened (n=19754)Records excluded (n=1328)Full-text articles assessed for eligibility (n=1248)Full-text excluded (n=80)Studies included in database (n=80)Studies included in dataset
  • Wrong intervention: n=192
  • Wrong study design (including non randomised trials): n=160
  • Wrong outcome: n=159
  • Wrong patient population: n=115
  • Conference, secondary paper or protocol: n=254
  • Not English language: n=92
  • Not an intervention trial: n=84
  • Duplicate: n=74
  • Relevant but no data: n=37
  • CR with no symptom outcome: n=30
  • Not available: n=18
  • Other: n=19
  • Not included in analysis: n=4
  • Included in NMA but not in psy vs ctr dataset: n=10


Further Information

  • The full protocol of the METAPSY project ↗
  • A paper summarizing main results of the Metapsy depression domain ↗
  • A network meta-analysis using the psychosis database ↗
  • Published meta-analyses using the depression database ↗
  • Published 'individual participant data' meta-analyses, based on the database ↗

Citation

Edel Mc Glanaghy , David Turner , Georgina A. Davis , Helen Sharpe , Nadine Dougall , Paul Morris , Wendy Prentice , Paul Hutton (2023) . Database of randomized clinical trials comparing psychological interventions for schizophrenia and psychosis with control conditions. Part of the Metapsy project (Version 23.1.4 ). URL docs.metapsy.org/databases/psychosis-psyctr. DOI https://doi.org/10.5281/zenodo.7782324 .

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